New genetic markers could improve early detection of drug-resistant tuberculosis

To many, tuberculosis (TB) may seem like a disease from a bygone era. But it still claims more than one million lives every year. And the problem is growing worse as Mycobacterium tuberculosisthe pathogen that causes TB, continues to evolve resistance to the antibiotics used to treat the disease. Now, researchers at San Diego State … Read more

Personal construct therapy found to be effective in reducing depression in women with fibromyalgia

May 9 2022 Fibromyalgia is a rheumatic disease of unknown origin, which is characterized by chronic pain and often accompanied by symptoms of depression. It mainly affects women, and there is no cure, but various treatments can help relieve the symptoms. Cognitive-behavioral psychological therapy has proven to be a useful tool in this area. Now, … Read more

Researchers investigate IgG antibodies against Mtb proteins in an Asian elephant cured of tuberculosis

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb); the leading cause of human death due to a single pathogen before the emergence of SARS-CoV-2. In elephants, the infections and deaths with TB have been reported worldwide, and elephant-to-human transmission has also been reported. Therefore, elephant TB is a concern for both conservation … Read more

Age-specific variation of asymptomatic COVID-19 infections

In a recent study posted to the medRxiv* preprint server, researchers evaluated asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection according to age. Study: Asymptomatic SARS-CoV-2 infection by age: A systematic review and meta-analysis. Image Credit: Andrii Vodolazhskyi / Shutterstock Asymptomatic coronavirus disease 2019 (COVID-19) infections have been a concerning subject in the design … Read more

National addiction treatment locator has outdated data and other critical flaws

At a psychiatric hospital in Michigan, Dr. Cara Poland’s patients were handed a sheet of paper to find follow-up care. The hospital had entered local ZIP codes on a website – run by the nation’s top substance use and mental health agency – and printed the resulting list of providers for patients to call. But … Read more

The study investigates the cause of lymphopenia as seen in COVID-19 patients

In a recent study posted to the Research Square* preprint server, researchers explored the underlying mechanism resulting in thymic atrophy and subsequent lymphopenia in coronavirus disease 2019 (COVID-19) patients. Study: SARS-CoV-2 and its variants, but not Omicron, induces severe thymic atrophy and impaired T cell development. Image Credit: erhanyelekci / Shutterstock Previous studies have reported … Read more

Mailed at-home disposal kits increase disposal rates of unused opioids after surgery

Mailed opioid disposal kits led to 60 percent of patients who had leftover opioid pain pills properly disposing of them after surgeries, according to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania. Just 43 percent of patients in this study who did not receive the kits disposed … Read more

Diagnostic performance of monocyte distribution width and other leukocyte parameters for SARS-CoV-2 and influenza infection

In a recent study posted to the Research Square* preprint server, researchers used a novel diagnostic screen, monocyte distribution width (MDW) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza infection. Study: Monocyte Distribution Width as a Pragmatic Diagnostic Screen for SARS-CoV-2 and Influenza Infection. Image Credit: Corona Borealis Studio / Shutterstock Background MDW, … Read more

Effectiveness of BNT162b2 third dose against Omicron-associated severe disease

In a recent study posted to the medRxiv* preprint server, researchers analyzed the effectiveness of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) BNT162b2 third vaccine dose against SARS-CoV-2 Omicron-induced severe infection nearly seven months post-vaccination. Study: Protection against omicron severe disease 0-7 months after BNT162b2 booster. Image Credit: peterschreiber.media/Shutterstock Background Following an increase in … Read more

What can chimpanzees tell us about cancer propensity in humans?

A recent study published in the renowned journal Cell Reports finds evidence for reduced functional activity of certain human cancer genes (such as breast cancer 2 gene or BRCA2), following the divergence from the chimpanzee-human last common ancestor. Study: Evidence for reduced BRCA2 functional activity in Homo sapiens after divergence from the chimpanzee-human last common … Read more